Kat is an out of work ski instructor who just wants to pack up her deceased mother's things, leave New York, and return to Aspen. Constancia is a talented but troubled young woman who just wants to start her first semester of college. In different shops across New York City, they and hundreds of other women of color try a new hair relaxer called "Reenu-You." Then things start to go horribly awry.

Within days, they find themselves covered in purple scab-like lesions--a rash that pulses, oozes, and spreads in spiral patterns. They are at the epicenter of a mysterious virus spreading throughout the city. As the outbreak spreads and new cases pop up in Black and Latino communities throughout New York, panic, anger, and questions fill the streets.

What is this virus and where did it come from?

Is it corporate malfeasance?

Or is this an orchestrated plot to kill minority women?

In the face of a terrifying and uncertain future, Kat, Constancia, and a small band of other affected women are forced to confront their deepest fears to save themselves and others. As the world crumbles around them, they will discover more about each other, learn about themselves, and draw strength to face the future together. Reenu-You looks at the social and political meanings of hair, female friendships, and viruses.