Dr. Isbell provides a unique personal and professional perspective on identifying and treating depression. From learning about how depression can take root to implementing permanent methods to restore wholeness, she helps her readers make informed decisions as they journey along their unique path to healing emotionally, physically, and spiritually. Included is a discussion of nutritional and botanical remedies provided in an easy-to-understand manner, with a review of a variety of medicines as well as conversation starters for readers and their primary health providers. She helps foster hope on the way to helping readers achieve relief and healing from depression.

Her review of the medication classes includes information to be aware of including side effects of medicines, both useful and adverse effects. She discusses medicines and spirituality, answering questions that patients of a variety of faith backgrounds have posed. For the Judeo Christian, scriptures for healing are included as well as positive affirmations for those of a different belief system.